CHARLOTTE – Atrium Health Sanger Heart & Vascular Institute’s heart transplant team is using new technology to keep hearts viable while being transported to a waiting heart transplant recipient.
The portable technology, called the TransMedics Organ Care System, expands the amount of time a donated heart can be suitable for transplant, helping make more donated hearts available for those who need them.
“Once a heart is removed from a deceased donor due to cardiac death, the portable system revives the heart and keeps it beating, infusing it with blood from the donor that is supplemented with nutrients and oxygen,” said Dr. Eric Skipper, a cardiothoracic heart transplant surgeon at Atrium Health Sanger Heart & Vascular Institute. “The system also allows us to carefully assess the heart’s functional quality and viability for transplant before we reach the operating room to perform the transplant.”
According to Skipper, TransMedics Organ Care System eliminates the time restraints that can require turning down a donated heart. Previously, the Sanger Heart & Vascular Institute transplant team could only accept donor hearts from within a 500-mile radius. That’s because there is a 4-hour cold storage limitation for the organ and the travel time between the deceased donor and a patient waiting for a transplant in Charlotte would exceed that. Now, with the use of the new technology, the donor pool has expanded because the heart can be kept viable for up to eight hours and be received from up to 1,000 miles away. It also allows for the acceptance of higher-risk hearts, including those from older donors and donors who are initially put on life support before withdrawing care, referred to as donation after cardiac death donors.
The first patient to receive a donated heart preserved via the new technology at Atrium Health had their transplant completed recently and is currently recovering in the hospital.
“This was a patient who was potentially looking at a long wait for an organ transplant,” Skipper said. “But because of the ability to utilize this technology, they were able to receive a heart very quickly.”
Sanger Heart & Vascular Institute is the only transplant center in the greater Charlotte region currently using this technology. The transplant team utilized Atrium Health's MedCenter Air to transport the team to and from the donor location.
“We were always limited to accepting organs from donors who suffered immediate brain death,” said Dr, Joseph Mishkin, an advanced heart failure transplant cardiologist at Sanger Heart & Vascular Institute. “We now can accept organs from donors who have suffered an irreversible brain injury but do not meet formal brain death criteria. In these instances, the family has decided to withdraw care. The donor’s organs can now be a life-saving gift for others.”
Across the U.S., more than 3,300 people are on the waiting list for a heart transplant and 95 of those are waiting in North Carolina, according to the U.S. Department of Health & Human Services Organ Procurement and Transplantation Network.
“We face a nationwide shortage of donated organs,” Mishkin said. “I expect this technology to transform the transplant industry, increasing the national donor supply and helping us transplant more patients in need.”
Gloss